CP-288886 is a cysLT1 receptor antagonist with a Ki value of 0.004 µM. CP-288886 exhibits comparable activity to Zafirlukast (HY-17492) and Pranlukast (HY-B0290). CP-288886 inhibits calcium mobilization with an IC50 of 0.0005 µM in human U937 cells. CP-288886 has high oral bioavailability. CP-288886 possesses anti-asthmatic activity in a guinea pig asthma model and can be used for the research of diseases such as asthma[1].
Molekulargewicht:
637.07
CAS Nummer:
[221332-74-7]
Formel:
C30H28ClF3N2O6S
Target-Kategorie:
Calcium Channel,Leukotriene Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
