CP-288886 is a cysLT1 receptor antagonist with a Ki value of 0.004 µM. CP-288886 exhibits comparable activity to Zafirlukast (HY-17492) and Pranlukast (HY-B0290). CP-288886 inhibits calcium mobilization with an IC50 of 0.0005 µM in human U937 cells. CP-288886 has high oral bioavailability. CP-288886 possesses anti-asthmatic activity in a guinea pig asthma model and can be used for the research of diseases such as asthma[1].
Molecular Weight:
637.07
CAS Number:
[221332-74-7]
Formula:
C30H28ClF3N2O6S
Target:
Calcium Channel,Leukotriene Receptor
Application Notes:
MCE Product type: Reference compound
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