Sotrastaurin (acetate), CAS [[908351-31-5]] Preis auf Anfrage

Produktübersicht

• Artikelname: Sotrastaurin (acetate), CAS [[908351-31-5]] Preis auf Anfrage
• Artikelnummer: MCE-HY-10540
• Hersteller Artikelnummer: HY-10540
• Alternativnummer: MCE-HY-10540-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: AEB071 (acetate)

Produktbeschreibung

Sotrastaurin (AEB071) acetate is a selective, orally active PKC inhibitor. Sotrastaurin acetate inactivates NF-kappaB by inhibiting PKC alpha, beta, theta, gamma subtypes, thereby reducing the transcription levels of immune response-related genes. Sotrastaurin acetate effectively inhibits alloreactive T cell proliferation, conventional T cell activation, as well as the production of pro-inflammatory cytokines and B lymphocytes. Sotrastaurin acetate also maintains the functional and phenotypic stability of regulatory T cells, enhances Foxp3 expression and restores the balance of helper T lymphocytes. Sotrastaurin acetate can prolong the survival time of allografts, and alleviate inflammatory responses and myasthenic symptoms by reducing anti-AChR antibody levels. Sotrastaurin acetate is widely used in studies related to kidney transplantation, psoriasis and myasthenia gravis[1][2][3].

Produkteigenschaften

• Molekulargewicht: 498.53
• CAS Nummer: [908351-31-5]
• Formel: C27H26N6O4
• Target-Kategorie: NF-kappaB,PKC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound