Calphostin C is a highly selective PKC inhibitor (IC50=0.05 µM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications[1][2][3].
Molekulargewicht:
790.76
Reinheit:
99.9
CAS Nummer:
[121263-19-2]
Formel:
C44H38O14
Target-Kategorie:
Antibiotic,Apoptosis,PKC
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten