Calphostin C is a highly selective PKC inhibitor (IC50=0.05 µM) and tumor apoptosis inducer. Calphostin C competitively binds to PKC and inhibits PKC-mediated phosphorylation signal transduction. Calphostin C restores Na+/K+ ATPase activity in the sciatic nerve of diabetic mice and improves neuropathy. Calphostin C can be used in the study of anti-tumor and diabetic complications[1][2][3].
Molecular Weight:
790.76
Purity:
99.9
CAS Number:
[121263-19-2]
Formula:
C44H38O14
Target:
Antibiotic,Apoptosis,PKC
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
