Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities[1][2][3].
Molekulargewicht:
382.93
Reinheit:
99.48
CAS Nummer:
[108050-82-4]
Formel:
C23H27ClN2O
Target-Kategorie:
Dopamine Receptor,Serotonin Transporter
Anwendungsbeschreibung:
MCE Product type: Reference compound
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