Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT1A (IC50=0.9 nM). Antipsychotic and antidepressant activities[1][2][3].
Molecular Weight:
382.93
Purity:
99.48
CAS Number:
[108050-82-4]
Formula:
C23H27ClN2O
Target:
Dopamine Receptor,Serotonin Transporter
Application Notes:
MCE Product type: Reference compound
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