SB-T-101141, CAS [[186348-05-0]] Preis auf Anfrage

Artikelnummer: MCE-HY-106159
Artikelname: SB-T-101141, CAS [[186348-05-0]] Preis auf Anfrage
Artikelnummer: MCE-HY-106159
Hersteller Artikelnummer: HY-106159
Alternativnummer: MCE-HY-106159-1UNIT
Hersteller: MedchemExpress
Kategorie: Biochemikalien
SB-T-101141 is a novel taxane. SB-T-101141 effectively induces a noncanonical ferroptosis to overcome Paclitaxel (HY-B0015) resistance of breast cancer. SB-T-101141 facilitates the production of iron and ferrous ions and ROS. SB-T-101141 stably binds to KHSRP to inhibit the iron-dependent expression of CISD1 related to iron homeostasis. SB-T-101141 synergistically enhances the iron-dependent activation of JNK and PERK pathways via KHSRP. SB-T-101141 suppresses breast tumor growth in MCF-7(PR)/MDA-MB-231(PR) or KHSRP knock-down MCF-7 xenograft mice model[1].
Molekulargewicht: 869.90
CAS Nummer: [186348-05-0]
Formel: C44H55NO17
Target-Kategorie: Ferroptosis,JNK,p38 MAPK,PERK,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung: MCE Product type: Reference compound