SB-T-101141, CAS [[186348-05-0]] Preis auf Anfrage

Product Overview

• Article Name: SB-T-101141, CAS [[186348-05-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-106159
• Supplier Catalog Number: HY-106159
• Alternative Catalog Number: MCE-HY-106159-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SB-T-101141 is a novel taxane. SB-T-101141 effectively induces a noncanonical ferroptosis to overcome Paclitaxel (HY-B0015) resistance of breast cancer. SB-T-101141 facilitates the production of iron and ferrous ions and ROS. SB-T-101141 stably binds to KHSRP to inhibit the iron-dependent expression of CISD1 related to iron homeostasis. SB-T-101141 synergistically enhances the iron-dependent activation of JNK and PERK pathways via KHSRP. SB-T-101141 suppresses breast tumor growth in MCF-7(PR)/MDA-MB-231(PR) or KHSRP knock-down MCF-7 xenograft mice model[1].

Product Properties

• Molecular Weight: 869.90
• CAS Number: [186348-05-0]
• Formula: C44H55NO17
• Target: Ferroptosis,JNK,p38 MAPK,PERK,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound