(R)-Crinecerfont, CAS [[2649012-21-3]]

Produktübersicht

• Artikelname: (R)-Crinecerfont, CAS [[2649012-21-3]]
• Artikelnummer: MCE-HY-106203B
• Hersteller Artikelnummer: HY-106203B
• Alternativnummer: MCE-HY-106203B-10MG,MCE-HY-106203B-5MG,MCE-HY-106203B-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (R)-SSR-125543

Produktbeschreibung

(R)-Crinecerfont is the R-enantiomer of Crinecerfont (HY-106203). Crinecerfont (SSR-125543) is an orally effective corticotropin-releasing factor receptor type-1 (CRF1 receptor) antagonist. Crinecerfont blocks CRF1 receptor signaling to reduce adrenocorticotropic hormone secretion. Crinecerfont improves hypothalamic-pituitary-adrenal axis negative feedback sensitivity in chronically stressed mice. Crinecerfont can be used for the research of chronic stress conditions and classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency[1][2]. Crinecerfont is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Produkteigenschaften

• Molekulargewicht: 483.04
• CAS Nummer: [2649012-21-3]
• Formel: C27H28ClFN2OS
• Target-Kategorie: CFTR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound