(rel)-MK 287, CAS [[143445-03-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: (rel)-MK 287, CAS [[143445-03-8]] Preis auf Anfrage
• Artikelnummer: MCE-HY-106899A
• Hersteller Artikelnummer: HY-106899A
• Alternativnummer: MCE-HY-106899A-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (rel)-L-680573

Produktbeschreibung

(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis[1].

Produkteigenschaften

• Molekulargewicht: 510.60
• CAS Nummer: [143445-03-8]
• Formel: C25H34O9S
• Target-Kategorie: Platelet-activating Factor Receptor (PAFR)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1