(rel)-MK 287, CAS [[143445-03-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-106899A
Supplier Catalog Number:
HY-106899A
Alternative Catalog Number:
MCE-HY-106899A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
(rel)-L-680573
(rel)-MK 287 ((rel)-L-680573) is a relative configuration of MK 287. MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED50 values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis[1].
Molecular Weight:
510.60
CAS Number:
[143445-03-8]
Formula:
C25H34O9S
Target:
Platelet-activating Factor Receptor (PAFR)
Application Notes:
MCE Product type: Reference compound1
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