GSK1034702 (Standard), CAS [[932373-87-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: GSK1034702 (Standard), CAS [[932373-87-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-107111R
• Hersteller Artikelnummer: HY-107111R
• Alternativnummer: MCE-HY-107111R-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GSK1034702 (Standard) is the analytical standard of GSK1034702 (HY-107111). This product is intended for research and analytical applications. GSK1034702 is an orally active and allosteric agonist of M1 mAChR (pEC50=8.1) that can cross the blood-brain barrier. GSK1034702 activates the Gq/11 protein-mediated signaling pathway, enhancing neuronal firing and long-term potentiation (LTP) in the CA1 region of the hippocampus. GSK1034702 can modulate hippocampal function, improve memory encoding in the nicotine withdrawal cognitive dysfunction model, and show pro-cognitive effects in rodents. GSK1034702 can be used for the study of the mechanisms of cognitive impairment diseases such as Alzheimers disease, and has certain peripheral M receptor activation-related side effects (such as gastrointestinal reactions)[1][2].

Produkteigenschaften

• Molekulargewicht: 333.40
• CAS Nummer: [932373-87-0]
• Formel: C18H24FN3O2
• Target-Kategorie: mAChR,Reference Standards

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference Standards