GSK1034702 (Standard), CAS [[932373-87-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-107111R
Supplier Catalog Number:
HY-107111R
Alternative Catalog Number:
MCE-HY-107111R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
GSK1034702 (Standard) is the analytical standard of GSK1034702 (HY-107111). This product is intended for research and analytical applications. GSK1034702 is an orally active and allosteric agonist of M1 mAChR (pEC50=8.1) that can cross the blood-brain barrier. GSK1034702 activates the Gq/11 protein-mediated signaling pathway, enhancing neuronal firing and long-term potentiation (LTP) in the CA1 region of the hippocampus. GSK1034702 can modulate hippocampal function, improve memory encoding in the nicotine withdrawal cognitive dysfunction model, and show pro-cognitive effects in rodents. GSK1034702 can be used for the study of the mechanisms of cognitive impairment diseases such as Alzheimers disease, and has certain peripheral M receptor activation-related side effects (such as gastrointestinal reactions)[1][2].
Molecular Weight:
333.40
CAS Number:
[932373-87-0]
Formula:
C18H24FN3O2
Target:
mAChR,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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