Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active kappa-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride has low permeability across the blood brain barrier and has peripheral anti-inflammatory actions. Asimadoline hydrochloride ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS)[1][2][3].
Molekulargewicht:
451.00
Reinheit:
99.57
CAS Nummer:
[185951-07-9]
Formel:
C27H31ClN2O2
Target-Kategorie:
Opioid Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
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