Asimadoline (EMD-61753) hydrochloride is an orally active, selective and peripherally active kappa-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant). Asimadoline hydrochloride has low permeability across the blood brain barrier and has peripheral anti-inflammatory actions. Asimadoline hydrochloride ameliorates allodynia in diabetic rats and has the potential for irritable bowel syndrome (IBS)[1][2][3].
Molecular Weight:
451.00
Purity:
99.57
CAS Number:
[185951-07-9]
Formula:
C27H31ClN2O2
Target:
Opioid Receptor
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
