A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3alpha and GSK-3beta. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain. A 1070722 decreases spontaneous locomotion[1][2].
Molekulargewicht:
362.31
Reinheit:
99.87
CAS Nummer:
[1384424-80-9]
Formel:
C17H13F3N4O2
Target-Kategorie:
GSK-3
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
