A 1070722 is a potent and selective glycogen synthase kinase 3 (GSK-3) inhibitor, with a Ki of 0.6 nM for both GSK-3alpha and GSK-3beta. A 1070722 can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in brain. A 1070722 decreases spontaneous locomotion[1][2].
Molecular Weight:
362.31
Purity:
99.87
CAS Number:
[1384424-80-9]
Formula:
C17H13F3N4O2
Target:
GSK-3
Application Notes:
MCE Product type: Reference compound
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