D-AP7 is a specific NMDA receptor antagonist with inhibitory activity against epileptiform activity. D-AP7 attenuated neuronal activation in spot activity by reducing the duration and number of exogenously induced bursts. D-AP7 also increased the amplitude of secondary action potentials, which may restore neuronal activity in some epileptiform bursts. D-AP7 showed anxiogenic effects and impaired memory consolidation in passive avoidance learning[1].
Molekulargewicht:
225.18
CAS Nummer:
[81338-23-0]
Formel:
C7H16NO5P
Target-Kategorie:
iGluR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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