D-AP7 is a specific NMDA receptor antagonist with inhibitory activity against epileptiform activity. D-AP7 attenuated neuronal activation in spot activity by reducing the duration and number of exogenously induced bursts. D-AP7 also increased the amplitude of secondary action potentials, which may restore neuronal activity in some epileptiform bursts. D-AP7 showed anxiogenic effects and impaired memory consolidation in passive avoidance learning[1].
Molecular Weight:
225.18
CAS Number:
[81338-23-0]
Formula:
C7H16NO5P
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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