GNE-490, CAS [[1033739-92-2]]

Produktübersicht

• Artikelname: GNE-490, CAS [[1033739-92-2]]
• Artikelnummer: MCE-HY-10812
• Hersteller Artikelnummer: HY-10812
• Alternativnummer: MCE-HY-10812-25MG,MCE-HY-10812-1MG,MCE-HY-10812-5MG,MCE-HY-10812-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

GNE-490, a (thienopyrimidin-2-yl)aminopyrimidine, is a potent pan-PI3K inhibitor with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta and PI3Kgamma, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50=750 nM). GNE-490 shows potent suppression efficacy profile against MCF7.1 breast cancer xenograft model[1].

Produkteigenschaften

• Molekulargewicht: 386.47
• Reinheit: 96.29
• CAS Nummer: [1033739-92-2]
• Formel: C18H22N6O2S
• Target-Kategorie: mTOR,PI3K

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound