HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 µM and an IC50 of 6 µM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS[1].
Molekulargewicht:
377.48
Reinheit:
99.89
CAS Nummer:
[162641-16-9]
Formel:
C22H27N5O
Target-Kategorie:
PGE synthase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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