HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 µM and an IC50 of 6 µM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS[1].
Molecular Weight:
377.48
Purity:
99.89
CAS Number:
[162641-16-9]
Formula:
C22H27N5O
Target:
PGE synthase
Application Notes:
MCE Product type: Reference compound
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