SU16f is a potent and selective PDGFRbeta inhibitor with IC50s of 10 nM, 140 nM, 2.29 µM for PDGFRbeta, VEGF-R2, FGF-R1, respectively[1]. Neutralization of PDGFRbeta receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration[2].
Molekulargewicht:
386.44
Reinheit:
99.36
CAS Nummer:
[251356-45-3]
Formel:
C24H22N2O3
Target-Kategorie:
PDGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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