SU16f is a potent and selective PDGFRbeta inhibitor with IC50s of 10 nM, 140 nM, 2.29 µM for PDGFRbeta, VEGF-R2, FGF-R1, respectively[1]. Neutralization of PDGFRbeta receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration[2].
Molecular Weight:
386.44
Purity:
99.36
CAS Number:
[251356-45-3]
Formula:
C24H22N2O3
Target:
PDGFR
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted