Cevidoplenib, CAS [[1703788-21-9]]

Produktübersicht

• Artikelname: Cevidoplenib, CAS [[1703788-21-9]]
• Artikelnummer: MCE-HY-109082
• Hersteller Artikelnummer: HY-109082
• Alternativnummer: MCE-HY-109082-5MG,MCE-HY-109082-100MG,MCE-HY-109082-10MMX1ML,MCE-HY-109082-50MG,MCE-HY-109082-10MG,MCE-HY-109082-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: SKI-O-703

Produktbeschreibung

Cevidoplenib (SKI-O-703) is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SKI-O-592. Cevidoplenib and SKI-O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SKI-O-592 potently inhibits multiple kinases with IC50s of 6.2 nM (Syk), 1.859 µM (Jak2), 5.807 µM (Jak3), 0.412 µM (RET), 0.687 µM (KOR), 1.783 µM (FLT3), 16.96 µM (FGFR1), 5.662 µM (FGFR3), and 0.709 µM (Pyk2), respectively[1][2][3].

Produkteigenschaften

• Molekulargewicht: 473.53
• Reinheit: 99.58
• CAS Nummer: [1703788-21-9]
• Formel: C25H27N7O3
• Target-Kategorie: Syk

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound