Cevidoplenib, CAS [[1703788-21-9]]

Product Overview

• Article Name: Cevidoplenib, CAS [[1703788-21-9]]
• Biozol Catalog Number: MCE-HY-109082
• Supplier Catalog Number: HY-109082
• Alternative Catalog Number: MCE-HY-109082-5MG,MCE-HY-109082-100MG,MCE-HY-109082-10MMX1ML,MCE-HY-109082-50MG,MCE-HY-109082-10MG,MCE-HY-109082-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: SKI-O-703

Product Description

Cevidoplenib (SKI-O-703) is an orally available inhibitor of spleen tyrosine kinase (Syk), with potential anti-inflammatory and immunomodulating activities. Cevidoplenib is also the mesylate form of SKI-O-592. Cevidoplenib and SKI-O-592 inhibits BCR-mediated survival, proliferation, and differentiation of B cells. And SKI-O-592 potently inhibits multiple kinases with IC50s of 6.2 nM (Syk), 1.859 µM (Jak2), 5.807 µM (Jak3), 0.412 µM (RET), 0.687 µM (KOR), 1.783 µM (FLT3), 16.96 µM (FGFR1), 5.662 µM (FGFR3), and 0.709 µM (Pyk2), respectively[1][2][3].

Product Properties

• Molecular Weight: 473.53
• Purity: 99.58
• CAS Number: [1703788-21-9]
• Formula: C25H27N7O3
• Target: Syk

Application Notes

• Application Notes: MCE Product type: Reference compound