CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM) while maintaining 230-fold selectivity over GRK5 (IC50=7.09 µM) and more than 2500-fold selectivity over GRK1 (IC50=87.3 µM), PKA, and ROCK1. CCG258208 hydrochloride can be used in heart failure research[1].
Molekulargewicht:
488.94
Reinheit:
98.05
Formel:
C24H26ClFN4O4
Target-Kategorie:
G Protein-coupled Receptor Kinase (GRK)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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