NBI 35965 (hydrochloride), CAS [[1782228-59-4]]

Produktübersicht

• Artikelname: NBI 35965 (hydrochloride), CAS [[1782228-59-4]]
• Artikelnummer: MCE-HY-110056
• Hersteller Artikelnummer: HY-110056
• Alternativnummer: MCE-HY-110056-10MG,MCE-HY-110056-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NBI 35965 hydrochloride is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 hydrochloride does not inhibit CRF2. NBI 35965 hydrochloride reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 hydrochloride shows anxiolytic effects[1][2].

Produkteigenschaften

• Molekulargewicht: 437.79
• CAS Nummer: [1782228-59-4]
• Formel: C21H23Cl3N4
• Target-Kategorie: CRFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound