NBI 35965 (hydrochloride), CAS [[1782228-59-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-110056
Supplier Catalog Number:
HY-110056
Alternative Catalog Number:
MCE-HY-110056-10MG,MCE-HY-110056-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
NBI 35965 hydrochloride is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 hydrochloride does not inhibit CRF2. NBI 35965 hydrochloride reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 hydrochloride shows anxiolytic effects[1][2].
Molecular Weight:
437.79
CAS Number:
[1782228-59-4]
Formula:
C21H23Cl3N4
Target:
CRFR
Application Notes:
MCE Product type: Reference compound
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