(E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 µM and 3 µM, for CaMKIIdelta monomer and CaMKIIdelta dodecamer. (E)-KN-93 phosphate binds competitively with Ca2+/CaM, and disrupts their interaction with CaMK II, and thus inhibits the CaMK II activation[1].
Molekulargewicht:
599.03
Reinheit:
99.85
CAS Nummer:
[1188890-41-6]
Formel:
C26H32ClN2O8PS
Target-Kategorie:
CaMK
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten