NAB2, CAS [[1504588-00-4]]

Produktübersicht

• Artikelname: NAB2, CAS [[1504588-00-4]]
• Artikelnummer: MCE-HY-110174
• Hersteller Artikelnummer: HY-110174
• Alternativnummer: MCE-HY-110174-100MG,MCE-HY-110174-10MMX1ML,MCE-HY-110174-1MG,MCE-HY-110174-5MG,MCE-HY-110174-25MG,MCE-HY-110174-50MG,MCE-HY-110174-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

NAB2 is a neuroprotectant that targets the small GTPase Rab1a. NAB2 selectively binds to the GDP-bound form of Rab1a and protects multiple cell types from alpha-synuclein toxicity by increasing Rab1a expression. Rab1a regulates ER-to-Golgi trafficking and mediates endosomal trafficking events of the E3 ubiquitin ligase Rsp5/Nedd4. NAB2 stimulates ubiquitination of related proteins in a Nedd4-dependent manner and rescues alpha-synuclein-associated trafficking defects associated with early-onset Parkinsons disease[1][2][3].

Produkteigenschaften

• Molekulargewicht: 389.88
• Reinheit: 99.69
• CAS Nummer: [1504588-00-4]
• Formel: C23H20ClN3O
• Target-Kategorie: alpha-synuclein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1