CM037 is a highly selective and competitive ALDH1A1 inhibitor (IC50=4.6 µM). CM037 blocks the catalytic activity of ALDH1A1, thereby inhibiting the activation of the downstream HIF-1alpha/VEGF pathway. CM037 is mainly used to study the ALDH1A1-mediated regulation of cancer stem cells (CSCs) and angiogenesis, especially in breast cancer, showing the potential to inhibit tumor angiogenesis and stem cell characteristics[1][2].
Molekulargewicht:
431.57
Reinheit:
99.55
CAS Nummer:
[896795-60-1]
Formel:
C21H25N3O3S2
Target-Kategorie:
Aldehyde Dehydrogenase (ALDH)
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
