Sitaxsentan (sodium), CAS [[210421-74-2]]

Artikelnummer: MCE-HY-11103
Artikelname: Sitaxsentan (sodium), CAS [[210421-74-2]]
Artikelnummer: MCE-HY-11103
Hersteller Artikelnummer: HY-11103
Alternativnummer: MCE-HY-11103-50MG,MCE-HY-11103-10MG,MCE-HY-11103-5MG,MCE-HY-11103-100MG,MCE-HY-11103-10MMX1ML
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: IPI 1040 (sodium), TBC11251 (sodium)
Sitaxsentan sodium (IPI 1040 sodium, TBC11251 sodium) is a potent, selective and orally activeendothelin A receptor (ETA) antagonist with an IC50 of 1.4 nM and a Ki of 0.43 nM. Sitaxsentan sodium exhibits an IC50 for the ETB receptor of as high as 9800 nM. Sitaxsentan sodium inhibits ET-1-induced phosphoinositide turnover. Sitaxsentan sodium can significantly alleviate pulmonary arterial hypertension (PAH) symptoms. Sitaxsentan sodium can be used for the study of PAH[1][2][3][4][5].
Molekulargewicht: 476.89
Reinheit: 98.83
CAS Nummer: [210421-74-2]
Formel: C18H14ClN2NaO6S2
Target-Kategorie: Endothelin Receptor
Anwendungsbeschreibung: MCE Product type: Reference compound