Sitaxsentan (sodium), CAS [[210421-74-2]]

Product Overview

• Article Name: Sitaxsentan (sodium), CAS [[210421-74-2]]
• Biozol Catalog Number: MCE-HY-11103
• Supplier Catalog Number: HY-11103
• Alternative Catalog Number: MCE-HY-11103-50MG,MCE-HY-11103-10MG,MCE-HY-11103-5MG,MCE-HY-11103-100MG,MCE-HY-11103-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: IPI 1040 (sodium), TBC11251 (sodium)

Product Description

Sitaxsentan sodium (IPI 1040 sodium, TBC11251 sodium) is a potent, selective and orally activeendothelin A receptor (ETA) antagonist with an IC50 of 1.4 nM and a Ki of 0.43 nM. Sitaxsentan sodium exhibits an IC50 for the ETB receptor of as high as 9800 nM. Sitaxsentan sodium inhibits ET-1-induced phosphoinositide turnover. Sitaxsentan sodium can significantly alleviate pulmonary arterial hypertension (PAH) symptoms. Sitaxsentan sodium can be used for the study of PAH[1][2][3][4][5].

Product Properties

• Molecular Weight: 476.89
• Purity: 98.83
• CAS Number: [210421-74-2]
• Formula: C18H14ClN2NaO6S2
• Target: Endothelin Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound