Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IkappaBalpha phosphorylation and NFkappaB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFkappaB pathways[1].
Molekulargewicht:
218.21
CAS Nummer:
[906366-79-8]
Formel:
C12H10O4
Target-Kategorie:
MMP,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
