YM-355179 (fumarate), CAS [[887647-69-0]] Preis auf Anfrage

Produktübersicht

• Artikelname: YM-355179 (fumarate), CAS [[887647-69-0]] Preis auf Anfrage
• Artikelnummer: MCE-HY-111198
• Hersteller Artikelnummer: HY-111198
• Alternativnummer: MCE-HY-111198-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

YM-355179 fumarate is a newly synthesized selective CCR3 antagonist with the potential to inhibit eosinophil-related allergic inflammatory diseases. YM-355179 can effectively inhibit the binding of CCL11 and CCL5 to CCR3-expressing cells, with IC50 values of 7.6 nM and 24 nM respectively. In functional experiments, YM-355179 can inhibit CCL11-induced intracellular Ca(2+) influx, chemotaxis and eosinophil degranulation, IC50 The values are 8.0 nM, 24 nM and 29 nM respectively[1].

Produkteigenschaften

• Molekulargewicht: 618.65
• CAS Nummer: [887647-69-0]
• Formel: C33H35FN4O7
• Target-Kategorie: Endogenous Metabolite

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound