YM-355179 (fumarate), CAS [[887647-69-0]] Preis auf Anfrage

Product Overview

• Article Name: YM-355179 (fumarate), CAS [[887647-69-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-111198
• Supplier Catalog Number: HY-111198
• Alternative Catalog Number: MCE-HY-111198-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

YM-355179 fumarate is a newly synthesized selective CCR3 antagonist with the potential to inhibit eosinophil-related allergic inflammatory diseases. YM-355179 can effectively inhibit the binding of CCL11 and CCL5 to CCR3-expressing cells, with IC50 values of 7.6 nM and 24 nM respectively. In functional experiments, YM-355179 can inhibit CCL11-induced intracellular Ca(2+) influx, chemotaxis and eosinophil degranulation, IC50 The values are 8.0 nM, 24 nM and 29 nM respectively[1].

Product Properties

• Molecular Weight: 618.65
• CAS Number: [887647-69-0]
• Formula: C33H35FN4O7
• Target: Endogenous Metabolite

Application Notes

• Application Notes: MCE Product type: Reference compound