GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARgamma, exhibiting a Ki of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPARgamma. GQ-16 is a partial agonist of PPARgamma with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain[1].
Molekulargewicht:
418.30
Reinheit:
98.12
CAS Nummer:
[870554-67-9]
Formel:
C19H16BrNO3S
Target-Kategorie:
PPAR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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