GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARgamma, exhibiting a Ki of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPARgamma. GQ-16 is a partial agonist of PPARgamma with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain[1].
Molecular Weight:
418.30
Purity:
98.12
CAS Number:
[870554-67-9]
Formula:
C19H16BrNO3S
Target:
PPAR
Application Notes:
MCE Product type: Reference compound
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