VH285-PEG4-C4-Cl, CAS [[1799506-07-2]]

Produktübersicht

• Artikelname: VH285-PEG4-C4-Cl, CAS [[1799506-07-2]]
• Artikelnummer: MCE-HY-111997
• Hersteller Artikelnummer: HY-111997
• Alternativnummer: MCE-HY-111997-10MG,MCE-HY-111997-100MG,MCE-HY-111997-10MMX1ML,MCE-HY-111997-5MG,MCE-HY-111997-50MG,MCE-HY-111997-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: HaloPROTAC 3

Produktbeschreibung

VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 µM[1].

Produkteigenschaften

• Molekulargewicht: 799.42
• Reinheit: 98
• CAS Nummer: [1799506-07-2]
• Formel: C41H55ClN4O8S
• Target-Kategorie: E3 Ligase Ligand-Linker Conjugates

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound