VH285-PEG4-C4-Cl, CAS [[1799506-07-2]]

Product Overview

• Article Name: VH285-PEG4-C4-Cl, CAS [[1799506-07-2]]
• Biozol Catalog Number: MCE-HY-111997
• Supplier Catalog Number: HY-111997
• Alternative Catalog Number: MCE-HY-111997-10MG,MCE-HY-111997-100MG,MCE-HY-111997-10MMX1ML,MCE-HY-111997-5MG,MCE-HY-111997-50MG,MCE-HY-111997-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: HaloPROTAC 3

Product Description

VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 µM[1].

Product Properties

• Molecular Weight: 799.42
• Purity: 98
• CAS Number: [1799506-07-2]
• Formula: C41H55ClN4O8S
• Target: E3 Ligase Ligand-Linker Conjugates

Application Notes

• Application Notes: MCE Product type: Reference compound