(S,R,S)-AHPC-Me, CAS [[1948273-02-6]]

Artikelnummer: MCE-HY-112078
Artikelname: (S,R,S)-AHPC-Me, CAS [[1948273-02-6]]
Artikelnummer: MCE-HY-112078
Hersteller Artikelnummer: HY-112078
Alternativnummer: MCE-HY-112078-25MG,MCE-HY-112078-500MG,MCE-HY-112078-1G,MCE-HY-112078-50MG,MCE-HY-112078-100MG,MCE-HY-112078-5G,MCE-HY-112078-250MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
Alternative Synonym: VHL ligand 2, E3 ligase Ligand 1A
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 [2].
Molekulargewicht: 444.60
Reinheit: 99.96
CAS Nummer: [1948273-02-6]
Formel: C23H32N4O3S
Target-Kategorie: Ligands for E3 Ligase
Anwendungsbeschreibung: MCE Product type: Reference compound