(S,R,S)-AHPC-Me, CAS [[1948273-02-6]]

Product Overview

• Article Name: (S,R,S)-AHPC-Me, CAS [[1948273-02-6]]
• Biozol Catalog Number: MCE-HY-112078
• Supplier Catalog Number: HY-112078
• Alternative Catalog Number: MCE-HY-112078-25MG,MCE-HY-112078-500MG,MCE-HY-112078-1G,MCE-HY-112078-50MG,MCE-HY-112078-100MG,MCE-HY-112078-5G,MCE-HY-112078-250MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: VHL ligand 2, E3 ligase Ligand 1A

Product Description

(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 [2].

Product Properties

• Molecular Weight: 444.60
• Purity: 99.96
• CAS Number: [1948273-02-6]
• Formula: C23H32N4O3S
• Target: Ligands for E3 Ligase

Application Notes

• Application Notes: MCE Product type: Reference compound