IDH889, CAS [[1429179-07-6]]

Produktübersicht

• Artikelname: IDH889, CAS [[1429179-07-6]]
• Artikelnummer: MCE-HY-112289
• Hersteller Artikelnummer: HY-112289
• Alternativnummer: MCE-HY-112289-100MG,MCE-HY-112289-25MG,MCE-HY-112289-5MG,MCE-HY-112289-10MMX1ML,MCE-HY-112289-50MG,MCE-HY-112289-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

IDH889 is an orally available, brain penetrant, allosteric and mutant specific inhibitor of isocitrate dehydrogenase 1 (IDH1). IDH889 has potent selectivity for IDH1 R132* mutations, with IC50s of 0.02 µM, 0.072 µM and 1.38 µM for IDH1R132H, IDH1R132C and IDH1wt, respectively. IDH889 shows potent cellular inhibition of R-2-hydroxyglutarate (2-HG) production with an IC50 of 0.014 µM[1].

Produkteigenschaften

• Molekulargewicht: 436.48
• Reinheit: 99.96
• CAS Nummer: [1429179-07-6]
• Formel: C23H25FN6O2
• Target-Kategorie: Isocitrate Dehydrogenase (IDH)

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound