SB 220025 (tri(hydrochloride)), CAS [[197446-75-6]] Preis auf Anfrage
Artikelnummer:
MCE-HY-112291A
Hersteller Artikelnummer:
HY-112291A
Alternativnummer:
MCE-HY-112291A-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
SB 220025 trihydrochloride is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 trihydrochloride also inhibits p56Lck and PKC with IC50 values of 3.5 and 2.89 µM, respectively. SB 220025 trihydrochloride inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 trihydrochloride effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation[1][2].
Molekulargewicht:
447.76
CAS Nummer:
[197446-75-6]
Formel:
C18H22Cl3FN6
Target-Kategorie:
p38 MAPK,PKC,Src
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
