SB 220025 (tri(hydrochloride)), CAS [[197446-75-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-112291A
Supplier Catalog Number:
HY-112291A
Alternative Catalog Number:
MCE-HY-112291A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SB 220025 trihydrochloride is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM). SB 220025 trihydrochloride also inhibits p56Lck and PKC with IC50 values of 3.5 and 2.89 µM, respectively. SB 220025 trihydrochloride inhibits the expression of IL-8 gene in response to globular adiponectin (gAd), reduces inflammatory cytokine production and inhibits angiogenesis. SB 220025 trihydrochloride effectively prevents the progression of arthritis in a chronic inflammatory disease model and can be used in the study of inflammation[1][2].
Molecular Weight:
447.76
CAS Number:
[197446-75-6]
Formula:
C18H22Cl3FN6
Target:
p38 MAPK,PKC,Src
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
