GSK2646264 (Compound 44) is a potent and selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.1. GSK2646264 also inhibits other kinases with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, LCK, LRRK2, GSK3beta, JAK2, VEGFR2, Aurora B and Aurora A, respectively. GSK2646264 is penetrable into the epidermis and dermis of the skin[1].
Molekulargewicht:
374.48
Reinheit:
98.39
CAS Nummer:
[1398695-47-0]
Formel:
C24H26N2O2
Target-Kategorie:
Aurora Kinase,GSK-3,JAK,LRRK2,Src,Syk,VEGFR
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten