GSK2646264 (Compound 44) is a potent and selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.1. GSK2646264 also inhibits other kinases with pIC50 values of 5.4, 5.4, 5.3, 5, 4.5, LCK, LRRK2, GSK3beta, JAK2, VEGFR2, Aurora B and Aurora A, respectively. GSK2646264 is penetrable into the epidermis and dermis of the skin[1].
Molecular Weight:
374.48
Purity:
98.39
CAS Number:
[1398695-47-0]
Formula:
C24H26N2O2
Target:
Aurora Kinase,GSK-3,JAK,LRRK2,Src,Syk,VEGFR
Application Notes:
MCE Product type: Reference compound
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