MA242 is a specific dual inhibitor of MDM2 and NFAT1. MA242 directly binds both MDM2 and NFAT1 with high affinity, induces their protein degradation, and inhibits NFAT1-mediated transcription of MDM2. MA242 induces apoptosis in pancreatic cancer cell lines regardless of p53 status[1].
Molekulargewicht:
579.98
Reinheit:
99.37
CAS Nummer:
[1049704-18-8]
Formel:
C26H21ClF3N3O5S
Target-Kategorie:
Apoptosis,MDM-2/p53
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
